Ingredient Library
Copper-binding tripeptide (glycyl-L-histidyl-L-lysine, copper complex)

GHK-Cu Copper Serum

Also known as GHK-Cu, Copper Tripeptide, Blue Copper Peptide

INCI name · Copper Tripeptide-1

GHK-Cu is the copper-bound tripeptide that made copper peptides an icon of fine skincare — used for the look of firmer, smoother, more radiant skin. For external cosmetic use only.

If copper peptides have a flagship, this is it. GHK-Cu — listed on an ingredient panel as Copper Tripeptide-1 — is a tiny three-amino-acid sequence bound to a single copper ion, and it is the reason a whole category of serums carries that unmistakable pale-blue cast.

This page keeps to what is honest about it: what the ingredient is, why formulators treasure it, the appearance areas it's used for, and how to wear it. It describes a cosmetic, not a treatment — everything here is about the look and feel of skin, not a promise of any effect.

Used for the look of
4 appearance contexts · hover one to read the note. For external cosmetic use only.

What Copper Tripeptide-1 actually is

The peptide half is glycyl-L-histidyl-L-lysine — three amino acids, abbreviated GHK. The copper half is a single copper(II) ion the peptide holds like a clasp; together they form the complex the INCI name calls Copper Tripeptide-1. That bound copper is what gives a well-made GHK-Cu serum its characteristic blue tint straight out of the bottle.

It is a small, water-loving molecule, which is why it slots so naturally into a lightweight leave-on serum. In our formula it sits at the considered heart of a simple routine rather than being buried in a long ingredient list.

Why it earned its reputation

Copper peptides became a quiet status ingredient because of how skin looks and feels after consistent use in a good routine — supple, smooth, evenly finished. That reputation is cosmetic and about appearance; GHK-Cu is prized by formulators and enthusiasts as the elegant, grown-up choice when a serum should feel refined rather than aggressive.

It layers gracefully. Because it is gentle in feel and plays nicely with the matrikine peptides in our Firming & Elasticity collection, it is a natural anchor for a peptide-forward shelf.

Reading a copper-peptide label

On an ingredient panel, look for Copper Tripeptide-1 — that is the INCI name for GHK-Cu. A faint blue color in the bottle is normal and expected for a copper-peptide serum; it comes from the bound copper, not a dye.

As with any copper peptide, a clean, focused formula tells you more than a crowded one. Ours is built around the peptide with a short, legible supporting cast.

How to use it

External use only. After cleansing, smooth a few drops over the face and neck morning and evening, then follow with moisturizer. Copper peptides are generally kept in their own step rather than mixed in the palm with strong acids or high-strength vitamin C. Patch-test on the inner arm before first use and discontinue if irritation occurs. Store cool and out of direct sun.

Common questions

What is GHK-Cu on an ingredient list?

It appears under its INCI name, Copper Tripeptide-1 — the copper-bound complex of the tripeptide glycyl-L-histidyl-L-lysine.

Why is the serum blue?

The pale-blue color is the bound copper ion itself, not an added dye. It's a normal, expected trait of a genuine copper-peptide serum.

Can I use it with my other actives?

Copper peptides are usually kept in their own step. Many people simply use GHK-Cu on one part of the day and stronger acids or vitamin C on another, so the routine stays comfortable.


Browse cosmetics
Pairs beautifully with
Copper Peptide Renewal Cream ↗Matrixyl 3000 ↗Palmitoyl Tripeptide-1 ↗Oligopeptide-1 Renewal Serum ↗
Reference

This is a cosmetic ingredient profile. It describes the active and the appearance of skin — the look and feel — not a treatment, a claim of any effect, or a recommendation for a medical use. These products are cosmetics and are not intended to diagnose, treat, cure, or prevent any disease. For external cosmetic use only.