Matrixyl 3000
Also known as Matrixyl 3000, Pal-GHK + Pal-GQPR
INCI name · Palmitoyl Tripeptide-1 & Palmitoyl Tetrapeptide-7
A duo of matrikine peptides in one lightweight serum — for the look of firmer, bouncier skin and a smoother, more even surface. For external cosmetic use only.
Matrixyl 3000 is not a single molecule but a partnership: two matrikine peptides — Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 — chosen to be used together. It is the modern counterpart to the original single-peptide Matrixyl.
The appeal of a duo is balance. Where a solo peptide brings one voice, this pairing is formulated for a rounded, resilient-looking result. Everything below is about appearance and feel, described honestly.
A partnership, not a single peptide
On an ingredient panel Matrixyl 3000 shows up as two names side by side: Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7. Both are lipidated matrikine peptides — short sequences with a palmitoyl tail that helps them sit in a serum.
Each of those peptides also lives on its own in our collection, so you can think of Matrixyl 3000 as the ready-made pairing and the two singles as the à-la-carte versions.
Why formulators reach for the duo
Pairing a tripeptide with a tetrapeptide is a way to build a serum that feels complete on its own. The two are formulated to complement each other, supporting the look of firmer, bouncier skin and a smoother, more even-looking surface with regular use.
It stays lightweight and layers cleanly under moisturizer, which is why it's such a comfortable centerpiece for a firming routine.
How it fits with the rest of the shelf
Matrixyl 3000 sits happily alongside copper peptides (used in their own step) and the brightening serums (used at a different time of day). If you already run the two singles separately, you likely don't need the duo as well — pick the format that suits your routine.
How to use it
External use only. Smooth a few drops over clean skin morning and evening before moisturizer. Keep copper peptides and strong acids in their own steps for comfort. Patch-test on the inner arm before first use and discontinue if irritation occurs. Store cool and out of direct sun.
Common questions
Two matrikine peptides: Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7, formulated to be used together.
It's your preference. Matrixyl 3000 is the convenient pre-paired serum; the singles let you layer each peptide on its own. Running both the duo and the singles isn't necessary.
No — the original Matrixyl is Palmitoyl Pentapeptide-4 alone. Matrixyl 3000 is the tripeptide-plus-tetrapeptide pairing.
This is a cosmetic ingredient profile. It describes the active and the appearance of skin — the look and feel — not a treatment, a claim of any effect, or a recommendation for a medical use. These products are cosmetics and are not intended to diagnose, treat, cure, or prevent any disease. For external cosmetic use only.